abstract：Background:Domiciliary noninvasive ventilation (NIV) use in stable hypercarbic COPD is becoming increasingly widespread. However, treatment compliance criteria and factors related to compliance remain to be defined. Methods:This research was designed as a prospective, cross-sectional, multicenter real-life study. Chro...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Yazar EE,Özlü T,Sarıaydın M,Taylan M,Ekici A,Aydın D,Coşgun İG,Durmuş Koçak N

更新日期：2018-08-10 00:00:00

abstract：Purpose:This study aimed to measure the true burden of COPD by calculating incremental direct and indirect costs. Direct medical resource use, productivity metrics, and COPD-specific resource use and costs were also evaluated. Patients and methods:This was a retrospective, observational, matched cohort study using adm...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Patel JG,Coutinho AD,Lunacsek OE,Dalal AA

更新日期：2018-07-30 00:00:00

abstract：Purpose:Previous studies have described the incidence, risk factors, and outcomes for patients with acute exacerbations of COPD (AECOPD) developing acute kidney injury (AKI). However, little is known about the differences between community-acquired AKI (CA-AKI) and hospital-acquired AKI (HA-AKI) in patients with AECOPD...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Cao CC,Chen DW,Li J,Ma MQ,Chen YB,Cao YZ,Hua X,Shao W,Wan X

更新日期：2018-07-17 00:00:00

abstract：Background:The DYNAGITO study was a Phase IIIb, randomized, double-blind, multicenter, active-controlled, parallel-group, 52-week study designed to determine the efficacy and safety of tiotropium and olodaterol combination therapy (TIO+OLO 5/5 μg) versus tiotropium monotherapy (TIO 5 μg) for reducing moderate-to-severe...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ichinose M,Nishimura M,Akimoto M,Kurotori Y,Zhao Y,de la Hoz A,Mishima M

更新日期：2018-07-13 00:00:00

abstract：Background:Although studies have examined the relationship between metabolic syndrome (MetS) and COPD, the incidence of MetS in individuals with COPD has not specifically been investigated. This study aimed to evaluate the incidence of MetS in subjects with airway obstruction using data from a community-based cohort. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kim CY,Park Y,Leem AY,Chung KS,Jung JY,Park MS,Kim YS

更新日期：2018-06-28 00:00:00

abstract：Background:The risk of dying of lung cancer is up to eightfold higher in patients with COPD than in age- and gender-matched controls. The aim of this study was to investigate the factors associated with lung cancer in a large cohort of COPD patients from primary care centers. Methods:To analyze whether age, gender, so...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Sandelin M,Mindus S,Thuresson M,Lisspers K,Ställberg B,Johansson G,Larsson K,Janson C

更新日期：2018-06-06 00:00:00

abstract：Aim:The aim of the current study was to assess the serum levels of trace minerals/heavy metals in COPD patients with and without pulmonary hypertension (PH) and to investigate their correlations to demographic, clinical, and biochemical variables. Materials and methods:This cross-sectional study was performed in Van Y...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Asker S,Asker M,Yeltekin AC,Aslan M,Ozbay B,Demir H,Turan H

更新日期：2018-05-31 00:00:00

abstract：Introduction:Biomass smoke exposure (BSE) is a recognized cause of COPD particularly in rural areas. However, little research has been focused on BSE in suburban areas. Objective:The aim of this study was to determine the prevalence of COPD, respiratory symptoms (RS) and BSE in women living in a suburban area of Mexic...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ramírez-Venegas A,Velázquez-Uncal M,Pérez-Hernández R,Guzmán-Bouilloud NE,Falfán-Valencia R,Mayar-Maya ME,Aranda-Chávez A,Sansores RH

更新日期：2018-05-25 00:00:00

abstract：Rationale:COPD has been perceived as being a disease of older men. However, >7 million women are estimated to live with COPD in the USA alone. Despite a growing body of literature suggesting an increasing burden of COPD in women, the evidence is limited. Objectives:To assess and synthesize the available evidence among...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ntritsos G,Franek J,Belbasis L,Christou MA,Markozannes G,Altman P,Fogel R,Sayre T,Ntzani EE,Evangelou E

更新日期：2018-05-10 00:00:00

abstract：Aim:Six-minute walking test distance (6MWD) and body mass index, obstruction, dyspnea and exercise (BODE) index are measures of functional status in COPD patients, but require space, time and patient's compliance. Exhaled volatile organic compounds (VOCs) analysis via electronic nose is a quick and easy method that has...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Finamore P,Pedone C,Scarlata S,Di Paolo A,Grasso S,Santonico M,Pennazza G,Antonelli Incalzi R

更新日期：2018-05-01 00:00:00

abstract：Purpose:Education on the self-management of COPD has been shown to improve patients' quality of life and reduce hospital admissions. This study aimed to assess the feasibility of a pilot, pragmatic COPD Chronic Care (CCC) education program led by registered respiratory therapists and determine the CCC's impact on hospi...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Collinsworth AW,Brown RM,James CS,Stanford RH,Alemayehu D,Priest EL

更新日期：2018-04-24 00:00:00

abstract：Background:Static hyperinflation is known to be increased during moderate acute exacerbations of chronic obstructive pulmonary disease (COPD) (AECOPD), but few data exist in patients with severe exacerbations of COPD. The role of dynamic hyperinflation during exacerbations is unclear. Methods:In a prospective, observa...

journal_title：International journal of chronic obstructive pulmonary disease

authors： van Geffen WH,Kerstjens HA

更新日期：2018-04-18 00:00:00

abstract：Background:COPD is considered an independent risk factor for lung cancer. COPD and lung cancer are both very heterogeneous diseases, and the study herein investigates the link between COPD phenotypes and specific histological subtypes of lung cancer. Methods:This case-control study comprised 2,283 patients with newly ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wang W,Xie M,Dou S,Cui L,Zheng C,Xiao W

更新日期：2018-04-13 00:00:00

abstract：Introduction:Understanding the breadth of patients' support needs is important for the delivery of person-centered care, particularly in progressive long-term conditions such as chronic obstructive pulmonary disease (COPD). Existing reviews identify important aspects of managing life with COPD with which patients may n...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Gardener AC,Ewing G,Kuhn I,Farquhar M

更新日期：2018-03-26 00:00:00

abstract：Background:Previous studies have suggested that β2-adrenergic receptor (ADRB2) is associated with COPD. However, the role of genetic polymorphisms in ADRB2 on COPD has not been evaluated yet. Methods:In this study, SNaPshot genotyping, luciferase assay, chromatin immunoprecipitation and real-time polymerase chain reac...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Li JX,Fu WP,Zhang J,Zhang XH,Sun C,Dai LM,Zhong L,Yu L,Zhang YP

更新日期：2018-03-16 00:00:00

abstract：Background:Few studies have examined changes in the pain experience of patients with COPD and predictors of pain in these patients. Objectives:The objectives of the study were to examine whether distinct groups of COPD patients could be identified based on changes in the occurrence and severity of pain over 12 months ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bentsen SB,Miaskowski C,Cooper BA,Christensen VL,Henriksen AH,Holm AM,Rustøen T

更新日期：2018-03-06 00:00:00

abstract：Purpose:Chest physiotherapy is an important tool in the treatment of COPD. Intrapulmonary percussive ventilation (IPV) and high-frequency chest wall oscillation (HFCWO) are techniques designed to create a global percussion of the lung which removes secretions and probably clears the peripheral bronchial tree. We tested...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Nicolini A,Grecchi B,Ferrari-Bravo M,Barlascini C

更新日期：2018-02-16 00:00:00

abstract：Background and objectives:Cognitive impairment is a common extrapulmonary comorbidity in COPD patients. The default mode network (DMN) plays a critical role in maintaining the normal activities of humans, and its function can be evaluated by resting state functional magnetic resonance imaging. The aim of this study was...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hu X,Wang H,Tu Y,Fei M,Yin M,Fei G,Yu Y

更新日期：2018-02-07 00:00:00

abstract：:COPD is a worsening condition that leads to a pathologic degeneration of the respiratory system. It represents one of the most important causes of mortality and morbidity in the world, and it is characterized by the presence of associated comorbidity. This article analyzes gastroesophageal reflux disease (GERD) and lo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bordoni B,Marelli F,Morabito B,Sacconi B,Caiazzo P,Castagna R

更新日期：2018-01-17 00:00:00

abstract：Rationale:Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) are caused by a variety of different etiologic agents. Our aim was to phenotype COPD exacerbations using imaging (chest X-ray [CXR] and computed tomography [CT]) and to determine the possible role of the blood tests (C-reactive protein [CRP...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Alotaibi NM,Chen V,Hollander Z,Hague CJ,Murphy DT,Leipsic JA,DeMarco ML,FitzGerald JM,McManus BM,Ng RT,Sin DD

更新日期：2018-01-08 00:00:00

abstract：Background:In contrast to cigarette smoking, the association between water pipe smoking and airway hyperresponsiveness remains widely unexplored. Methods:A bronchoprovocation challenge with mannitol was performed in young adults recruited at the University of Basel, Switzerland. Subjects were categorized as acute wate...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Scherr A,Schmidlin J,Albisser S,Tamm M,Stolz D

更新日期：2018-01-03 00:00:00

abstract：Background:Thirty-day readmission in COPD is common and costly, but potentially preventable. The emergency department (ED) may be a setting for COPD readmission reduction efforts. Objective:To better understand COPD readmission through the ED, ascertain factors associated with 30-day readmission through the ED, and id...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Rezaee ME,Ward CE,Nuanez B,Rezaee DA,Ditkoff J,Halalau A

更新日期：2017-12-27 00:00:00

abstract：:COPD is a complex, heterogeneous condition. Even in the early clinical stages, COPD carries a significant burden, with breathlessness frequently leading to a reduction in exercise capacity and changes that correlate with long-term patient outcomes and mortality. Implementation of an effective management strategy is re...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Ariel A,Altraja A,Belevskiy A,Boros PW,Danila E,Fležar M,Koblizek V,Fridlender ZG,Kostov K,Krams A,Milenkovic B,Somfay A,Tkacova R,Tudoric N,Ulmeanu R,Valipour A

更新日期：2017-12-21 00:00:00

abstract：Background:Endoscopic lung volume reduction (eLVR) is a therapeutic option for selected patients with COPD and severe emphysema. Infectious exacerbations are serious events in these vulnerable patients; hence, prophylactic antibiotics are often prescribed postinterventionally. However, data on the microbiological airwa...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Trudzinski FC,Seiler F,Wilkens H,Metz C,Kamp A,Bals R,Gärtner B,Lepper PM,Becker SL

更新日期：2017-12-19 00:00:00

abstract：Purpose:There is currently no measure to predict a treatability of long-acting β-2 agonist (LABA) or long-acting muscarinic antagonist (LAMA) in patients with chronic obstructive pulmonary disease (COPD). We aimed to build prediction models for the treatment response to these bronchodilators, in order to determine the ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kang J,Kim KT,Lee JH,Kim EK,Kim TH,Yoo KH,Lee JS,Kim WJ,Kim JH,Oh YM

更新日期：2017-12-12 00:00:00

abstract：Background and purpose:While the efficacy and safety of combined tiotropium and olodaterol in patients with COPD was established in a large clinical trial program, it is important to assess whether clinical data can be applied to geographic patient groups, particularly for East Asian patients who may have a different p...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bai C,Ichinose M,Lee SH,Lee KH,Jöns O,Bothner U,Zhao Y,Buhl R

更新日期：2017-11-20 00:00:00

abstract：Background:Patients with chronic obstructive pulmonary disease (COPD) often have poor health-related quality of life (HRQoL) that is disproportionate to their degree of airflow limitation. This study evaluated the association between St George's Respiratory Questionnaire for COPD (SGRQ-C) score and forced expiratory vo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lee H,Jhun BW,Cho J,Yoo KH,Lee JH,Kim DK,Lee JD,Jung KS,Lee JY,Park HY

更新日期：2017-11-13 00:00:00

abstract：:Smoking-related interstitial lung disease (ILD) consists of a heterogeneous group of disorders that are considered a distinct entity. The 2013 American Thoracic Society and European Respiratory Society recommendations classified respiratory bronchiolitis (RB)/RB-ILD and desquamative interstitial pneumonia (DIP) as smo...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Bak SH,Lee HY

更新日期：2017-11-01 00:00:00

abstract：Purpose:The aims of this study were to evaluate dynamic changes in heart size during the respiratory cycle using four-dimensional computed tomography (CT) and to understand the relationship of these changes to airflow limitation in smokers. Materials and methods:A total of 31 smokers, including 13 with COPD, underwent...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Xu Y,Yamashiro T,Moriya H,Tsubakimoto M,Tsuchiya N,Nagatani Y,Matsuoka S,Murayama S

更新日期：2017-10-26 00:00:00

abstract：BACKGROUND:There is conflicting information regarding the effects of selective and nonselective beta-blocker treatment in patients with COPD. PARTICIPANTS AND METHODS:This nested case-control study used the Taiwan National Health Insurance Research Database. We included COPD patients who used inhalation steroid and be...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Huang YL,Lai CC,Wang YH,Wang CY,Wang JY,Wang HC,Yu CJ,Chen L

更新日期：2017-10-11 00:00:00

abstract：BACKGROUND:COPD patients are often prescribed multiple medications for their respiratory disease and comorbidities. This can lead to complex medication regimens resulting in poor adherence, medication errors, and drug-drug interactions. The relationship between clinical outcomes and medication burden beyond medication ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Negewo NA,Gibson PG,Wark PA,Simpson JL,McDonald VM

更新日期：2017-10-06 00:00:00

abstract：BACKGROUND AND AIM:Patients with advanced chronic obstructive pulmonary disease (COPD) have poor quality of life. The aim of this study was to assess the effects of proactive palliative care on the well-being of these patients. TRIAL REGISTRATION:This trial is registered with the Netherlands Trial Register, NTR4037. ...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Duenk RG,Verhagen C,Bronkhorst EM,van Mierlo P,Broeders M,Collard SM,Dekhuijzen P,Vissers K,Heijdra Y,Engels Y

更新日期：2017-09-28 00:00:00

abstract：BACKGROUND AND OBJECTIVE:It is known that biomarkers of systemic inflammation are raised in COPD caused by tobacco (T-COPD) compared with healthy controls, but there is less information on the inflammatory status of subjects with COPD caused by biomass smoke (B-COPD). In addition, the possible (if any) differences in i...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Golpe R,Martín-Robles I,Sanjuán-López P,Pérez-de-Llano L,González-Juanatey C,López-Campos JL,Arellano-Orden E

更新日期：2017-09-01 00:00:00

abstract：BACKGROUND:Lung volume reduction (LVR) improves breathing mechanics by reducing hyperinflation. Lobar selection usually focuses on choosing the most destroyed emphysematous lobes as seen on an inspiratory CT scan. However, it has never been shown to what extent these densitometric CT parameters predict the least deflat...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Hetzel J,Boeckeler M,Horger M,Ehab A,Kloth C,Wagner R,Freitag L,Slebos DJ,Lewis RA,Haentschel M

更新日期：2017-08-30 00:00:00

abstract：OBJECTIVE:β-Blockers are safe and improve survival in patients with both congestive heart failure (CHF) and COPD. However, the superiority of different types of β-blockers is still unclear among patients with CHF and COPD. The association between β-blockers and CHF exacerbation as well as COPD exacerbation remains uncl...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Liao KM,Lin TY,Huang YB,Kuo CC,Chen CY

更新日期：2017-08-26 00:00:00

abstract：BACKGROUND:Pulmonary rehabilitation (PR) is recommended after a severe COPD exacerbation, but its short- and long-term effects on health care utilization have not been fully established. AIMS:The aims of this study were to evaluate patient compliance with a chronic disease management (CDM) program incorporating home-b...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Lalmolda C,Coll-Fernández R,Martínez N,Baré M,Teixidó Colet M,Epelde F,Monsó E

更新日期：2017-08-23 00:00:00

abstract：BACKGROUND:Recent studies that assessed the relevance of the blood eosinophil count as a biomarker in patients with COPD may have overestimated it because they included patients with asthma-COPD overlap syndrome (ACOS). We investigated the clinical implications of the blood eosinophil count in patients with non-ACOS CO...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Song JH,Lee CH,Kim JW,Lee WY,Jung JY,Park JH,Jung KS,Yoo KH,Park YB,Kim DK

更新日期：2017-08-17 00:00:00

abstract：:The purpose of this study was to compare the relative efficacy and safety of different antibiotic drugs and recommend superior regimens in the treatment of bronchitis. With respect to the antibiotic comparisons against quinolones in terms of intention-to-treat patients, we concluded that quinolones had advantages over...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Wang J,Xu H,Liu P,Li M

更新日期：2017-08-09 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Pulmonary Daoyin (PD) (evolved from ancient Chinese daoyin skills), is a rehabilitation technology that combines specially designed movements of the arms and body and controlled breathing exercises, to improve the physiological and psychological status of patients with chronic respiratory disea...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Zhang HL,Li JS,Yu XQ,Li SY,Halmurat U,Xie Y,Wang YF,Li FS,Wang MH

更新日期：2017-08-04 00:00:00

abstract：BACKGROUND:Cardiac autonomic modulation (CAM) is impaired in patients with stable COPD. Exacerbation aggravates the patients' health status and functional capacity. While the clinical and functional effects of exacerbation are known, no studies investigated CAM during exacerbation and whether there is a relationship be...

journal_title：International journal of chronic obstructive pulmonary disease

authors： Kabbach EZ,Mazzuco A,Borghi-Silva A,Cabiddu R,Agnoleto AG,Barbosa JF,de Carvalho Junior LCS,Mendes RG

更新日期：2017-07-28 00:00:00